Toxicities of 166holmium-chitosan in mice

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August undefined, 2024

WebApr 1, 2024 · The holmium/chitosan complex (Millican, Dong Wha Pharmaceutical Co., Seoul, Korea) was effective in treating small HCCs in a novel study based on 40 patients with single HCC < 3 cm in size with... WebFeb 1, 2012 · Chitosan cause loss of fat-soluble vitamins and block absorption of medicines such as birth control pills (Orr, 1999).This study was designed to investigate the hepato …

A pilot study of trans-arterial injection of 166Holmium-Chitosan ...

WebMar 1, 1998 · In this study, 166Ho was complexed to chitosan (Chit) which decreases the distribution of Ho into other tissues when applied intrahepatically. To investigate the single dose toxicity, mice were administered intravenously with 1 mCi/kg body weight of 166Ho … WebSep 20, 2024 · This study assessed the protective effects of selenium-chitosan (SC) against antioxidant and immune function-related damage induced by zearalenone (ZEN) in mice. In total, 150 female mice were allotted to five groups for a 30-day study. Control mice were fed a basal diet. Mice in the ZEN, ZEN-Se1, ZEN-Se2 and ZEN-Se3 groups were fed the basal … gold and black pfp

Antibacterial activity, acute toxicity and the effect of garlic and ...

WebDec 1, 1998 · Holmium-166-chitosan complex [0.75 mg of Ho(NO3)3 x 5H2O and 1 mg chitosan/ head] was administered intrahepatically to male rats. Radioactive … WebApr 8, 2024 · The use of silver nanoparticles (AgNPs) embedded in polymeric matrix has acquired special attention as a strategy to reduce metal toxicity without losing its antimicrobial effect. In this work, the green synthesis of AgNPs and their functionalization with chitosan (AgNPs@Chi) was performed, and their antifungal activity investigated … WebJul 9, 2024 · Chitosan possesses a high density of positive charges due to the protonation of amino groups and presents properties such as nontoxicity, biocompatibility and biodegradability (Luo and Wang, 2014 ). hbcu football jerseys

Oral gene delivery with chitosan–DNA nanoparticles generates

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WebNov 21, 2014 · Although chitosan is reported to be non-toxic, the in vivo toxicity assay demonstrated that the LD50 of chitosan is 16 g kg −1 in mice. Assessment of the toxicity … WebIn vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicity Authors Yoon H.Y.; Lee S.; Kim K.; Chang H.; Yhee J.Y.; Jeon S.; Shim M.K. Ewha Authors 김광명 SCOPUS Author ID 김광명 Issue Date 2024 Journal Title gold and black pc buildWebFeb 5, 2024 · The term mushroom refers to the fungal fruiting body. Anatomically, the prototypical mushroom comprises the stem and a cap with gills on the underside. However, the term may refer to many … gold and black pc

"WebThe level of radioactivity in blood, urinary and faecal excretion, and radioactivity distribution were examined. To determine the effect of chitosan in DW-166HC, 166Ho nitrate alone [0.1875 mg of Ho(NO3)3.5H2O] was administered into the prostate of male rats, and radioactivity distribution was examined using whole-body autoradiography. " - Toxicities of 166holmium-chitosan in mice

Toxicities of 166holmium-chitosan in mice

Frontiers Silver Chitosan Nanocomposites are Effective to …

WebChitosan is a cationic carbohydrate polymer that is commercially derived from the deacetylation of chitin obtained from seafood shells. The most widespread route of human exposure to chitosan is as a dietary … WebDec 1, 2005 · The fate of 166Ho-chitosan complex, a radiopharmaceutical drug for cancer therapy, was determined by studying its absorption, distribution and excretion in rats and …

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WebDec 1, 2024 · Fecal moisture was significantly increased in 9% males (up to 170%) and 9% females at all time points, in 3% males during week 6, and … http://allie.dbcls.jp/pair/166Ho;166Holmium.html

WebNov 21, 2014 · 2.4. Chronic toxicity assay of chitosan and its derivates in in vivo models. Chronic toxicity studies were carried out with chitosan and modified chitosan materials after peroral treatment at a dose of 30 mg kg −1 bw per day in Swiss albino mice. Experimental animals were divided into the following seven groups (n = 6). WebMar 1, 1998 · In this study, 166Ho was complexed to chitosan (Chit) which decreases the distribution of Ho into other tissues when applied intrahepatically. To investigate the …

WebApr 13, 2024 · The chitosan-coated nanoemulsions with TMZ showed the expected physicochemical characteristics and demonstrated safety and efficacy, reducing around 70% the tumor size compared to control mice, and presenting a tendency in mitotic index reduction, becoming an interesting approach to treat melanoma brain metastasis. ... To … WebApr 13, 2024 · The most successful medical intervention for preventing infectious diseases is still vaccination. This effective strategy has resulted in decreased mortality and extended life expectancy. However, there is still a critical need for novel vaccination strategies and vaccines. Antigen cargo delivery by nanoparticle-based carriers could promote superior …

WebSep 20, 2024 · This study assessed the protective effects of selenium-chitosan (SC) against antioxidant and immune function-related damage induced by zearalenone (ZEN) in mice. …

WebLee, W.Y. et al. Toxicities of 166Holmium-chitosan in mice. Arzneimittelforschung 48 , 300–304 ( 1998). CAS PubMed Google Scholar hbcu football kickoffWebApr 1, 2013 · The toxicity of chitosan nanoparticles needs to be evaluated in embryo development aspects because extensive research into their biomedical applications was based largely on the biodegradable and biocompatible profile of chitosan. ... The mice were housed in wire cages at 22 ± 1°C under a 12L:12D cycle with 70% humidity and fed ad … gold and black pensWebJan 1, 2024 · In an acute toxicity test, mice (n = 20, 10 male, 10 female) were administered a single dose of 10 g/kg BW of Lithothamnion sp. No mortality, or signs of toxicity were … gold and black party ideasWebDec 10, 2024 · This study was conducted to evaluate the subacute toxicity effect of Chitosan-alginate coated microparticle of Garcinia mangostana Linn extract’s oral administration. Fifty BALB/c mice were... hbcu football leagueWebApr 1, 2010 · The single dose toxicity of chitosan in rodents is low with reported values given in Table 3. This table also summarises repeat dose toxicity studies that have been performed with chitosan or related materials in rodents, rabbits and dogs using various parenteral and oral (gavage and dietary) routes. hbcu football players drafted 2020WebApr 1, 2024 · To evaluate the biological safety of chitosan nanoparticles, chronic toxicity study was conducted in Swiss albino mice. Briefly, the animals were divided into two groups of 5 each. Animals of group I were given corn oil in normal diet on alternative days and those of group II were fed with 0.5% dosage of void nanoparticles in water on ... gold and black pendant lightWebMay 11, 2024 · Disc diffusion method was used to test for activity against Escherichia coli ( E. coli) and Staphylococcus aureus ( S. aureus) with Fosbac as the positive control. Acute toxicity in mice through oral administration of the nanoparticles solution at … hbcu football players drafted 2021