WebThe tapasin-related protein TAPBPR is a novel component of the antigen processing and presentation pathway, which binds to MHC class I coupled with β 2-microglobulin.We describe six alternatively spliced TAPBPR transcripts from the TAPBPL gene and investigate three of these at a protein level. TAPBPR transcripts lacking exon 5 result in loss of the … WebJun 10, 2014 · Van Hateren, Andrew (2014) The tapasin-related protein (TAPBPR) binds MHC class I molecules (MHC I) with high affinity and functions in a similar fashion to …
The N‐terminal region of tapasin is required to stabilize the MHC …
WebTapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway. Boyle LH et al. Proceedings of the National Academy of Sciences of the United … WebNX_Q9BX59 - TAPBPL - Tapasin-related protein - Function. Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). bob faust chicago
Integrated analysis of mRNA-miRNA expression in Tilapia infected …
WebThis Human Tapasin-related protein (TAPBPL) ELISA Kit employs a two-site sandwich ELISA to quantitate TAPBPL in samples. An antibody specific for TAPBPL has been pre-coated … WebThe protein was induced at room temperature overnight and purified using nickel beads according to the standard protocol. The protein was further purified by gel filtration … WebJun 1, 2024 · Peptide presentation on MHC class I molecules (MHC-I) is central to mounting effective antiviral and antitumoral immune responses. The tapasin-related protein TAPBPR is an MHC-I peptide editor which shapes the final peptide repertoire displayed on … clipart for phone